Pancreas transplants are carried out under general anaesthetic. This means you'll be asleep and will not feel anything during the procedure.
A pancreas transplant operation can take 2 to 4 hours to complete.
If you also need a kidney transplant at the same time, the operation can take around 4 to 8 hours.
Your new pancreas should start to produce insulin straight away.
A small number of people with type 1 diabetes may have a slightly different procedure, where only the cells that produce insulin (islet cells) are transplanted from a donor pancreas into the liver.
This is called islet transplantation and is usually carried out under local anaesthetic, which means you're awake but the area being operated on is numbed. You may also be offered a sedative (medicine to help you relax).
A thin, flexible tube (catheter) is inserted through your tummy and liver into the vein that supplies the liver with blood. The donor islet cells are then injected into it.
If the operation is successful, the donor cells will start making insulin. This can help people who experience severe episodes of a dangerously low blood sugar level that occur without warning.
Insulin treatment is often still needed after the operation, but the episodes of low blood sugar should be easier to control.
As with a conventional pancreas transplant, you'll need to take medicine to stop your immune system attacking the donor islet cells.
For more information, see the National Institute for Health and Care Excellence (NICE) guidance on allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus.
Once the transplant is complete, you'll usually be moved to an intensive care unit (ICU) or a high dependency unit (HDU).
You'll be very closely looked after, and various tubes and machines that help monitor your health and support the functions of your body will be attached to you.